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消化在线: ESGE官方声明:结肠镜前的肠道准备

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背景目的:该指南是欧洲胃肠内镜学会(ESGE)的官方声明。目的是选择结肠镜前的肠道准备方案。
  方法:该指南根据有针对性的文献检索来确定结肠镜前肠道准备的证据支持。指南推荐内容的评估,发展和评级系统的分级采用的是推荐的强度和证据质量的
  主要推荐:
   (1)欧洲胃肠内镜学会推荐结肠镜检前低纤维饮食。(弱级推荐,中等质量证据)
   (2)欧洲胃肠内镜学会推荐4L聚乙二醇溶液分次服用方案(或者行肠镜当天肠道准备方案)作为常规肠道准备方案。2L聚乙二醇溶液分次服用方案(或肠镜当日肠道准备方案)加抗坏血酸盐或磷酸钠加柠檬酸镁为有效备选,尤其适用于门诊择期行肠镜的患者。对于肾衰竭患者,聚乙二醇溶液是肠道准备的唯一选择。肠道准备时间与行肠镜时间之间的间隔应该最短化,最长间隔不得超过4小时。(强力推荐,中等质量证据)
   (3)欧洲胃肠内镜学会建议出于安全性考虑,磷酸钠不能作为肠镜检查前肠道准备的常规用药。(强力推荐,低等质量证据)
  Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) guideline.BACKGROUND AND AIM: His Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the choice mongst regimens available for cleansing the colon in preparation for colonoscopy.METHODS: This Guideline is based on a targeted literature search to evaluate the evidence supporting the use of bowel preparation for colonoscopy. The Grading of
Recommendations Assessment, Development and Evaluation (GRADE) system was adopted to define the strength of recommendation and the quality of evidence.RESULTS: The main recommendations are as follows.(1)  The ESGE recommends a low-fiber diet on the day preceding colonoscopy (weak recommendation, moderate quality evidence).(2)  The ESGE recommends a split regimen of 4
L of polyethylene glycol (PEG) solution (or a same-day regimen in the case of afternoon colonoscopy) for routine bowel
preparation. A split regimen (or same-day regimen in the case of afternoon colonoscopy) of 2 L PEG plus ascorbate or of sodium picosulphate plus magnesium citrate may be valid alternatives, in particular for elective outpatient colonoscopy (strong recommendation, high quality evidence). In patients with renal failure, PEG is the only recommended bowel preparation. The delay between the last dose of bowel preparation and colonoscopy should be minimized and no longer than 4 hours (strong recommendation, moderate quality evidence). (3)  The ESGE advises against the routine use of sodium phosphate
for bowel preparation because of safety concerns (strong recommendation, low quality evidence).
  Ref: Hassan C, et al. Endoscopy. 2013;45(2):142-50. doi: 10.1055/s-0032-1326186. Epub 2013 Jan 18.

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